Saved by Science

The Hope and Promise of Synthetic Biology

Excerpt

The future of mankind is far from secure. I am among many who believe that humanity is in crisis; in particular, our personal health, the security of our food supply and the health of our environment all face potentially catastrophic challenges. Our health faces many unresolved dangers in the areas of cancer, infectious diseases and mental health. Rapid population growth and the many environmental challenges in our agricultural systems raise questions about how we will feed the world in the year 2050. Global warming and climate change are threatening our environments, and pollution is poisoning our land, lakes, rivers and oceans.

While these challenges are monumental and the future may appear bleak, there is hope. Imagine being able to:

  • Identify specific genetic mutations of a whole range of cancers and to develop personalized and specific therapies (i. e., cures), even at the patient’s bedside.
  • Modify the genetic mutation that predisposes people to suffer from schizophrenia, bipolar disease, severe depression or addictive disorders and to offer effective cures.
  • Respond to any viral outbreak (such as Ebola, Zika, AIDS, a nasty flu or COVID-19) with an effective vaccine produced in only days or even hours.
  • Grow nutritious, inexpensive, high-protein foods in the widest range of possible conditions of temperature, sunlight, water and fertility . . . or even on Mars.
  • Create real meat without killing animals or to produce real milk without milking cows.
  • Provide plants with nitrogen from the air instead of having to mine or chemically synthesize expensive nitrogen fertilizers.
  • Reverse global warming by removing carbon from the atmosphere and using it as an energy source or material for advanced manufacturing.
  • Use microbes to clean up lakes and rivers, removing lead, mercury and other toxic materials and returning our waterways to pristine condition.
  • Design specific microbes to clean up toxic-waste dumps, abandoned mines and industrial sites, and even to clean up disastrous oil spills.

 

A mere six or seven years ago, these imaginings would have been purely the stuff of science fiction. Today, we have realistic expectations that they’ll happen — and that they’ll be brought to market within a decade, maybe even less. These are the products of what some call the “fourth industrial revolution,” a marriage of computer science and newfound knowledge in biology, particularly genomics. This book is about that revolution, a new field of science called synthetic biology and the hope and promise that it offers for the future of mankind.

Description

Examines the evolution of synthetic biology and looks at the power of microbes to effect dramatic changes in three of the most pressing crises facing mankind: food, medicine, and climate.

Reviews

“Energetic and optimistic . . . With sensible language and peer-reviewed research, the author explores the present and coming needs regarding global health care, food security, and pollution and examines the history of genetically modified organisms . . . Encouraging advances in biology delineated through accessible, inviting writing. ” — Kirkus Reviews

“Over the next few decades we will learn how to edit life-forms by altering their DNA, much as we now edit stories and books using ABC’s. Poznansky gives us a sense of what this might mean for medicine, food, climate, and a myriad of human endeavors and challenges. He does so with grace and ease, such that any curious mind can comprehend. ” — Juan Enriquez, author of As the Future Catches You and co-author of Evolving Ourselves

Saved by Science is a terrific gateway into the fascinating world of synthetic biology. It outlines why we need these new genetic superpowers more than ever if we are to solve global challenges and continue our most exciting explorations, such as establishing thriving colonies on Mars. Mark Poznansky’s book is a tonic for anyone concerned about global hunger, energy, health, or climate. It turns out we’ve got the tools to address pretty much every challenge right at our fingertips — we just have to get to work. ” — Andrew Hessel, founder and president of Humane Genomics

“Synthetic biology promises to be the next important step in our application of DNA. Mark Poznansky not only introduces us to the incredible potential of constructing novel living organisms but also provides the context to ensure that the inevitable debate will be constructive. ” — Jay Ingram, science writer and broadcaster